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Category:Voicemodeling softwareDoes disuse muscle atrophy preferentially involve fast-twitch or slow-twitch muscle fibers?
Fast-twitch and slow-twitch fibers contribute in different ways to the gain or loss of muscle mass and the incidence of disuse muscle atrophy. In mice, we previously found that disuse muscle atrophy preferentially affects slow-twitch muscle fibers, based on muscle fiber type analysis and measurements of muscle size and force. To determine whether this is also true in humans, we investigated the association between muscle fiber type and disuse muscle atrophy in elderly men. In a case-control study involving 884 ambulant elderly men, we measured indexes of disuse muscle atrophy in the gluteus maximus, vastus lateralis, and lateral gastrocnemius muscles and compared these to indexes of muscle mass, fiber type, and strength in these muscles. Subjects were characterized into two groups based on whether or not they lost >5% of their muscle mass in one of these three muscles. In slow-twitch muscles, gluteus maximus and vastus lateralis, atrophy was highly associated with the loss of muscle mass. In contrast, in fast-twitch muscles, lateral gastrocnemius, atrophy was not associated with loss of muscle mass. Slow-twitch muscle mass and strength were more closely related to the amount of atrophy than fast-twitch muscle mass and strength. In the gluteus maximus and vastus lateralis, however, atrophy and decrease in muscle mass were associated with similar percentages of decline in type IIx (slow-twitch) and type IIa (fast-twitch) muscle fibers. In the lateral gastrocnemius, atrophy was not associated with a reduction in type IIx fibers. These results indicate that disuse muscle atrophy preferentially affects type II fibers in slow-twitch muscles and suggest that this is not true in fast-twitch muscles.Q:

What is the difference between “you would” and “you would be”?

I would like to know the differences between “you would” and “you would be”. Are they interchangeable or do they have some common use or not?

A:

“You would” is a passive form which could be used for the person doing the action. For example, if you were to take a picture of yourself walking, you could say “You would be in the picture, wouldn’t you”.

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